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Every English word that uses exactly these letters, straight from our dictionary.
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PKU
What These Words Mean
PKU noun
a genetic disorder of metabolism; lack of the enzyme needed to turn phenylalanine into tyrosine results in an accumulation of phenylalanine in the body fluids which causes various degrees of mental deficiency
Solving Jumble Words by Hand
Before reaching for a solver, try these anagram tricks: separate the vowels from the consonants, look for common endings such as -ING, -ED and -LY, test frequent letter pairs (TH, CH, ST, ER), and write the letters in a circle so your brain stops seeing the scrambled order. Most five-letter Jumble words fall to these techniques, and daily practice makes you dramatically faster.
Once you have all four words, the circled letters feed the final cartoon punchline. Enter those circled letters above and the solver will find multi-word answers too. For a full walkthrough see how to play Daily Jumble, or check today's answers.